Tuesday, 30 April 2019

Designer drugs to inhibit hepatitis A virus

Structure-based drug design revealed that a compound previously investigated for the treatment of head-and-neck cancer could function as a lead compound for the development of drugs to treat hepatitis A virus infection, according to a study publishing April 30 in the open-access journal PLOS Biology by Dan Su of Sichuan University, Zihe Rao of Tsinghua University, Xiangxi Wang of the Chinese Academy of Sciences, and colleagues.

* This article was originally published here

Galaxy Fold review: Should you pay $2,000 for Samsung's delayed folding phone tablet?

Samsung's new $1,980 Galaxy Fold has been making waves over the last two weeks, not necessarily for all the right reasons.

* This article was originally published here

Cable firm Altice USA scoops up streaming news site Cheddar

Cable-broadband operator Altice USA said Tuesday it was acquiring the youth-focused streaming news group Cheddar for $200 million.

* This article was originally published here

EPA reaffirms glyphosate safe for users as court cases grow

The Environmental Protection Agency reaffirmed Tuesday that a popular weed killer is safe for people, as legal claims mount from Americans who blame the herbicide for their cancer.

* This article was originally published here

Space station power shortage delays SpaceX supply run

A major power shortage at the International Space Station has delayed this week's SpaceX supply run.

* This article was originally published here

Can the effects of the ketogenic diet help prevent epilepsy after traumatic brain injury?

Neuroscientists led by Chris Dulla at Tufts University School of Medicine prevented the development of epileptic activity in mice after traumatic brain injury by using a drug that mimics the metabolic effects of the ketogenic diet. An advance copy of the study is published today in JCI Insight.

* This article was originally published here

Brain signaling proteins hit the road running

Surprisingly complex movements in an important neurotransmitter receptor may help explain the brain's unpredictable response to drugs, according to a new study. New research from an international team, published this week in the journal Neuron, has revealed that the resting state of signaling proteins are much more dynamic than previously thought.

* This article was originally published here

Computer scientists design way to close 'backdoors' in AI-based security systems

It sounds like a plot out of a spy novel, with a touch of cyberpunk: An agent approaches a secure location, protected by a facial recognition system, accessible only to a head of state or CEO. Flashing an unusually shaped earring, the agent tricks the system into thinking they're that VIP, opening the door and exposing the secrets inside. The key—an undetectable "sleeper cell" was placed inside the AI behind the security system months or years earlier to grant access to anyone wearing the specified jewelry.

* This article was originally published here

Study: Health care providers split on who should prescribe HIV prevention drug

Health care practitioners are split when it comes to opinions on which provider should take the lead in prescribing pre-exposure prophylaxis (PrEP), which is administered to people at high risk for HIV.

* This article was originally published here

Bio-based chemicals could reduce fossil fuel use

Petrochemicals, the oil- and gas-derived compounds that serve as the molecular backbones for much of modern commerce, commanded a $539.3 billion market value in 2018.

* This article was originally published here

Researchers identify causes and mechanisms of polycystic ovary syndrome using family-based genetic analysis

A first-of-its-kind study using family-based genetic analysis has confirmed a gene involved in male hormone production, DENND1A, plays a major role in the development of polycystic ovary syndrome (PCOS). The discovery will enable personalized medicine approaches to PCOS, including better disease prediction. The findings are available online in The Journal of Clinical Endocrinology & Metabolism.

* This article was originally published here

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Fetal alcohol spectrum disorder prevalence is very high in susceptible groups worldwide

A major new review of the world literature has found that Fetal Alcohol Spectrum Disorder (FASD) is 10 to 40 times higher in certain susceptible groups than the general population. These groups include children in care, people in correctional services or special education services, Aboriginal populations, and people using specialized clinical services.

* This article was originally published here

Egypt's rebounding tourism threatens Red Sea corals

In serene turquoise waters off Egypt's Red Sea coast, scuba divers ease among delicate pink jellyfish and admire coral—yet a rebounding tourism sector threatens the fragile marine ecosystem.

* This article was originally published here

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NEW D&G Dolce & Gabbana DG3274 3126 WHITE DOTS On BLACK EYEGLASSES 52mm Italy

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WARBY PARKER LAUREL EYEGLASS FRAMES OAK BARREL RX LENSES 52-17-140 NEW

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3 Refresh Plus Lubricant Eye Drops Dry Eye Relief Eye Care 70 Vials Each 03/20

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