Tuesday, 7 May 2019

3-D 'mini-gut' model reflects autoimmune response to gluten in celiac patient tissue

In pursuit of a novel tool for the research and treatment of celiac disease, scientists at the Mucosal Immunology and Biology Research Center (MIBRC) at Massachusetts General Hospital (MGH) have validated the use of intestinal organoids. These three-dimensional tissue cultures are miniature, simplified versions of the intestine produced in vitro. Taking tissue from duodenal biopsies of celiac and non-celiac patients, researchers created the "mini-guts" to explore how the gut epithelium and microbiota-derived molecules respond to gluten, a complex class of proteins found in wheat and other grains.

* This article was originally published here

Design flaws create security vulnerabilities for 'smart home' internet-of-things devices

Researchers at North Carolina State University have identified design flaws in "smart home" Internet-of-Things (IoT) devices that allow third parties to prevent devices from sharing information. The flaws can be used to prevent security systems from signaling that there has been a break-in or uploading video of intruders.

* This article was originally published here

Fat fruit flies: High-sugar diet deadens sweet tooth; promotes overeating, obesity in flies

Some research suggests that one reason people with obesity overeat is because they don't enjoy food—especially sweets—as much as lean people.

* This article was originally published here

Microsoft to turn next chapter in raising talk to conversations

On Monday at Build 2019, Microsoft's annual conference for developers, the company showed off the technology for a conversational engine, to integrate with voice assistant Cortana.

* This article was originally published here